Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation.
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| Title: | Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation. |
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| Authors: | Zhang X; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Xu J; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Genetics and Metabolism Department, The Children's Hospital, School of Medicine, Zhejiang University, National Clinical Research Center for Child Health, Hangzhou, China.; The Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China., Hu J; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Zhang S; National Institute of Biological Sciences,7 Science Park Road, Beijing, China., Hao Y; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; China National Center for Bioinformation, Beijing, China.; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, 100049, Beijing, China., Zhang D; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA., Qian H; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China., Wang D; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu.; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu.; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. dow003@health.ucsd.edu., Fu XD; Westlake Laboratory of Life Sciences and Biomedicine, School of Life Sciences and School of Medicine, Westlake University, Hangzhou, Zhejiang, China. fuxiangdong@westlake.edu.cn. |
| Source: | Nature communications [Nat Commun] 2024 Jul 17; Vol. 15 (1), pp. 6031. Date of Electronic Publication: 2024 Jul 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-50298-w |
