CMPK2 Promotes CD4+ T Cell Activation and Apoptosis through Modulation of Mitochondrial Dysfunction in Systemic Lupus Erythematosus.

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Title: CMPK2 Promotes CD4+ T Cell Activation and Apoptosis through Modulation of Mitochondrial Dysfunction in Systemic Lupus Erythematosus.
Authors: Tan YN; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China.; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China.; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, PR China., Jiang GG; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China.; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China.; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, PR China., Meng XW; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China.; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China.; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, PR China., Lu ZY; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China.; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China.; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, PR China., Yan-Ma; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Li J; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Nan-Xiang; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Sun XG; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Wang Q; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Wang X; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China., Jia XY; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, PR China.; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei, Anhui, PR China., Zhang M; Division of Life Sciences and Medicine, Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, PR China. doczhangmin@ustc.edu.cn.
Source: Cell biochemistry and biophysics [Cell Biochem Biophys] 2024 Dec; Vol. 82 (4), pp. 3547-3557. Date of Electronic Publication: 2024 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0283 (Electronic) Linking ISSN: 10859195 NLM ISO Abbreviation: Cell Biochem Biophys Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-0283
DOI:10.1007/s12013-024-01443-1