Metformin suppresses esophageal cancer progression through the radiation‑induced cellular senescence of cancer‑associated fibroblasts.

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Title: Metformin suppresses esophageal cancer progression through the radiation‑induced cellular senescence of cancer‑associated fibroblasts.
Authors: Sugimoto Y; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Okamoto K; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Saito H; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Yamaguchi T; Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa 920‑8530, Japan., Kinoshita J; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Nakamura K; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Takino T; Division of Education for Global Standard, Institute of Liberal Arts and Science, Kanazawa University, Kanazawa, Ishikawa 920‑1192, Japan., Endo Y; Central Research Resource Branch, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa 920‑1192, Japan., Ninomiya I; Department of Surgery, Fukui Prefectural Hospital, Fukui 910‑0846, Japan., Ohta T; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan., Inaki N; Department of Gastrointestinal Surgery, Division of Cancer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa 920‑8641, Japan.
Source: Oncology reports [Oncol Rep] 2024 Oct; Vol. 52 (4). Date of Electronic Publication: 2024 Aug 02.
Publication Type: Journal Article
Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2431 (Electronic) Linking ISSN: 1021335X NLM ISO Abbreviation: Oncol Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1791-2431
DOI:10.3892/or.2024.8788