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Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality.

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Title: Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality.
Authors: Wang R; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Gomez Salazar M; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Pruñonosa Cervera I; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Coutts A; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK., French K; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Pinto MM; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Gohlke S; Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany., García-Martín R; Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC (CNB-CSIC), Campus-UAM, Madrid, Spain., Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research University of Oxford, Oxford, UK., Kourtzelis I; Hull York Medical School, York Biomedical Research Institute, University of York, York, UK., Stimson RH; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Bénézech C; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Christian M; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK., Schulz TJ; Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Gudmundsson EF; Icelandic Heart Association, Kopavogur, Iceland., Jennings LL; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Gudnason VG; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Chavakis T; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Paul Langerhans Institute Dresden, Helmholtz Zentrum München, University Hospital and Faculty of Medicine Technische Universität Dresden, Dresden, Germany., Morton NM; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK., Emilsson V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Michailidou Z; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK. zoi.michailidou@ntu.ac.uk.; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK. zoi.michailidou@ntu.ac.uk.
Source: Nature communications [Nat Commun] 2024 Aug 29; Vol. 15 (1), pp. 7483. Date of Electronic Publication: 2024 Aug 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gomez+Salazar+M%22">Gomez Salazar M</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Pruñonosa+Cervera+I%22">Pruñonosa Cervera I</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Coutts+A%22">Coutts A</searchLink>; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22French+K%22">French K</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Pinto+MM%22">Pinto MM</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Gohlke+S%22">Gohlke S</searchLink>; Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22García-Martín+R%22">García-Martín R</searchLink>; Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC (CNB-CSIC), Campus-UAM, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Blüher+M%22">Blüher M</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Schofield+CJ%22">Schofield CJ</searchLink>; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kourtzelis+I%22">Kourtzelis I</searchLink>; Hull York Medical School, York Biomedical Research Institute, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Stimson+RH%22">Stimson RH</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Bénézech+C%22">Bénézech C</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Christian+M%22">Christian M</searchLink>; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Schulz+TJ%22">Schulz TJ</searchLink>; Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Potsdam-Rehbrücke, Nuthetal, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gudmundsson+EF%22">Gudmundsson EF</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Jennings+LL%22">Jennings LL</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gudnason+VG%22">Gudnason VG</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Chavakis+T%22">Chavakis T</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.; Paul Langerhans Institute Dresden, Helmholtz Zentrum München, University Hospital and Faculty of Medicine Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Morton+NM%22">Morton NM</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Emilsson+V%22">Emilsson V</searchLink>; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Michailidou+Z%22">Michailidou Z</searchLink>; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK. zoi.michailidou@ntu.ac.uk.; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Clifton, Nottingham, UK. zoi.michailidou@ntu.ac.uk.
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