Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome.
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| Title: | Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome. |
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| Authors: | Mensah JA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Johnson K; Contract Site of the National Institute of Neurological Disorders and Stroke Epilepsy Therapy Screening Program, Salt Lake City, Utah, USA., Freeman T; Center for Human Toxicology, Salt Lake City, Utah, USA., Reilly CA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.; Center for Human Toxicology, Salt Lake City, Utah, USA., Rower JE; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.; Center for Human Toxicology, Salt Lake City, Utah, USA., Metcalf CS; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.; Contract Site of the National Institute of Neurological Disorders and Stroke Epilepsy Therapy Screening Program, Salt Lake City, Utah, USA., Wilcox KS; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.; Contract Site of the National Institute of Neurological Disorders and Stroke Epilepsy Therapy Screening Program, Salt Lake City, Utah, USA. |
| Source: | Epilepsia [Epilepsia] 2024 Oct; Vol. 65 (10), pp. 3100-3114. Date of Electronic Publication: 2024 Aug 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1528-1167 |
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| DOI: | 10.1111/epi.18104 |