MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial.
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| Title: | MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial. |
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| Authors: | Janiaud P; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Zecca C; Neurology Clinic Lugano, Neurocenter of Southern Switzerland, Lugano, MS Center, Switzerland.; Faculty of Biomedical Sciences, Università Della Svizzera Italiana (USI), Lugano, Switzerland., Salmen A; Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Bochum, Germany., Benkert P; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Schädelin S; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Orleth A; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland., Demuth L; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland., Maceski AM; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland., Granziera C; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.; Department of Medicine and Biomedical Engineering, Translational Imaging in Neurology Basel, University Hospital Basel, University of Basel, Basel, Switzerland., Oechtering J; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland., Leppert D; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Derfuss T; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland., Achtnichts L; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland., Findling O; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland., Roth P; Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Lalive P; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland., Uginet M; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland., Müller S; Department of Neurology, Cantonal Hospital St, Gallen, St. Gallen, Switzerland., Pot C; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and, University of Lausanne, Lausanne, Switzerland., Hoepner R; Department of Neurology, Bern University Hospital and University of Bern, Bern, Switzerland., Disanto G; Neurology Clinic Lugano, Neurocenter of Southern Switzerland, Lugano, MS Center, Switzerland., Gobbi C; Neurology Clinic Lugano, Neurocenter of Southern Switzerland, Lugano, MS Center, Switzerland., Rooshenas L; Bristol Population Health Science Institute, University of Bristol, Bristol, UK., Schwenkglenks M; Health Economics Facility, Department of Public Health, University of Basel, Basel, Switzerland.; Institute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland., Lambiris MJ; Health Economics Facility, Department of Public Health, University of Basel, Basel, Switzerland.; Institute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland., Kappos L; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Kuhle J; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland., Yaldizli Ö; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; MS Centre, Neurologic Clinic and Policlinic, University Hospital Basel, Basel, Switzerland.; Department of Medicine and Biomedical Engineering, Translational Imaging in Neurology Basel, University Hospital Basel, University of Basel, Basel, Switzerland., Hemkens LG; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland. lars.hemkens@usb.ch.; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland. lars.hemkens@usb.ch. |
| Source: | Trials [Trials] 2024 Sep 11; Vol. 25 (1), pp. 607. Date of Electronic Publication: 2024 Sep 11. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1745-6215 |
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| DOI: | 10.1186/s13063-024-08454-6 |
