Pharmacokinetics of Efmoroctocog alfa by Two-Compartment Model Highlights Hemophilia A Patients with Biphasic Decay, Long Mean Residence Time, and Beta Half-Life.
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| Title: | Pharmacokinetics of Efmoroctocog alfa by Two-Compartment Model Highlights Hemophilia A Patients with Biphasic Decay, Long Mean Residence Time, and Beta Half-Life. |
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| Authors: | Morfini M; Italian Association of Hemophilia Centers (AICE), I 20120 Milan, Italy., Peyvandi F; Department of Pathophysiology and Transplantation, University of Milan, Fondazione IRCSS Ca' Granda Maggiore Hospital, 'Angelo Bianchi Bonomi', I 20120 Milan, Italy., Mancuso ME; Center for Thrombosis and Hemorrhagic Diseases, IRCCS ' Humanitas Research Hospital', Rozzano, I 20142 Milan, Italy., Marchesini E; Hemophilia Centre, Internal and Cardiovascular Medicine, 'Santa Maria della Misericordia' University Hospital, I 06100 Perugia, Italy., Tagliaferri A; Regional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, I 43100 Parma, Italy., Gualtierotti R; Department of Pathophysiology and Transplantation, University of Milan, Fondazione IRCSS Ca' Granda Maggiore Hospital, 'Angelo Bianchi Bonomi', I 20120 Milan, Italy., Castaman G; Department of Oncology, Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, I 50139 Florence, Italy., Pollio B; Regional Reference Centre for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, 'Regina Margherita' Children Hospital, I 10100 Turin, Italy., Santoro C; Department of Hematology, University Hospital Policlinico 'Umberto I', I 00100 Rome, Italy., Banov L; Regional Reference Centre for Hemorrhagic Diseases, IRCCS Istituto 'Giannina Gaslini', I 16100 Genoa, Italy., Napolitano M; Hematology Unit, Thrombosis and Hemostasis Reference Regional Centre, University of Palermo, I 90100 Palermo, Italy., Preti PS; Department of Internal Medicine and Therapeutics, University of Pavia, I 27100 Pavia, Italy., Santoro RC; Regional Reference Centre for Hemophilia and Coagulation Diseases, Azienda Ospedaliera Pugliese 'Ciaccio', I 88100 Catanzaro, Italy., Coppola A; Regional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, I 43100 Parma, Italy., Linari S; Department of Oncology, Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, I 50139 Florence, Italy., Santagostino E; SOBI, SE-11276 Stockholm, Sweden., Bernardi F; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, I 44121 Ferrara, Italy. |
| Source: | Journal of clinical medicine [J Clin Med] 2024 Aug 23; Vol. 13 (17). Date of Electronic Publication: 2024 Aug 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2077-0383 |
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| DOI: | 10.3390/jcm13174986 |
