The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy volunteers.
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| Title: | The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy volunteers. |
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| Authors: | Messaoudene M; Axe Cancer, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada., Ferreira S; Da Volterra, Paris, France., Saint-Lu N; Da Volterra, Paris, France., Ponce M; Axe Cancer, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada., Truntzer C; Platform of Transfer in Biological Oncology, Georges François Leclerc Cancer Center-Unicancer, Dijon, France.; UMR INSERM 1231, Dijon, France., Boidot R; Molecular Biology, Georges François Leclerc Cancer Center-Unicancer, Dijon, France., Le Bescop C; Da Volterra, Paris, France., Loppinet T; Da Volterra, Paris, France., Corbel T; Da Volterra, Paris, France., Féger C; Da Volterra, Paris, France.; Medical, EMI Biotech, Paris, France., Bertrand K; Da Volterra, Paris, France., Elkrief A; Axe Cancer, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Hemato-Oncology Division, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, QC, Canada., Isaksen M; Bio-Me, Oslo, Norway., Vitry F; Da Volterra, Paris, France., Sablier-Gallis F; Da Volterra, Paris, France., Andremont A; Da Volterra, Paris, France., Bod L; Krantz Family Cancer Center, Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ghiringhelli F; Department of Medical Oncology, Georges François Leclerc Cancer Center-Unicancer, Dijon, France., de Gunzburg J; Da Volterra, Paris, France., Routy B; Axe Cancer, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada. Bertrand.routy@umontreal.ca.; Hemato-Oncology Division, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, QC, Canada. Bertrand.routy@umontreal.ca. |
| Source: | Nature communications [Nat Commun] 2024 Sep 15; Vol. 15 (1), pp. 8083. Date of Electronic Publication: 2024 Sep 15. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-52373-8 |
