Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial.
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| Title: | Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial. |
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| Authors: | Gianferrari G; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy.; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy., Cuoghi Costantini R; Unit of Statistical and Methodological Support to Clinical Research, Azienda Ospedaliero-Universitaria, Modena 41121, Italy., Crippa V; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milan 20122, Italy.; Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Milan 20122, Italy., Carra S; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy., Bonetto V; Research Center for ALS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy., Pansarasa O; Cellular Model and Neuroepigenetics Unit, IRCCS Mondino Foundation, Pavia 27100, Italy., Cereda C; Department of Pediatrics, Center of Functional Genomics and Rare diseases, 'V. Buzzi' Children's Hospital, Milan 20154, Italy., Zucchi E; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy.; Neurosciences PhD Program, University of Modena and Reggio Emilia, Modena 41121, Italy., Martinelli I; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy.; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena 41121, Italy., Simonini C; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy., Vicini R; Unit of Statistical and Methodological Support to Clinical Research, Azienda Ospedaliero-Universitaria, Modena 41121, Italy., Fini N; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy., Trojsi F; Department of Advanced Medical and Surgical Sciences, ALS Center, Università degli Studi della Campania L. Vanvitelli, Naples 80138, Italy., Passaniti C; Department of Advanced Medical and Surgical Sciences, ALS Center, Università degli Studi della Campania L. Vanvitelli, Naples 80138, Italy., Ticozzi N; Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy.; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan 20122, Italy., Doretti A; Department of Neurology, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy., Diamanti L; Neuroncology and Neuroinflammation Unit, IRCCS Mondino Foundation, Pavia 27100, Italy., Fiamingo G; Neuroncology and Neuroinflammation Unit, IRCCS Mondino Foundation, Pavia 27100, Italy., Conte A; Department of Aging, Neurological, Orthopedic and Head-Neck Sciences, Adult NEMO Clinical Center, Unit of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome 00168, Italy., Dalla Bella E; 3rd Neurology Unit and Motor Neuron Disease Centre, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan 20133, Italy., D'Errico E; Department of Basic Medical Sciences, ALS Center, Neurosciences and Sense Organs, University of Bari, Bari 70124, Italy., Scarian E; Cellular Model and Neuroepigenetics Unit, IRCCS Mondino Foundation, Pavia 27100, Italy., Pasetto L; Research Center for ALS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy., Antoniani F; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy., Galli V; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy., Casarotto E; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milan 20122, Italy.; Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Milan 20122, Italy., D'Amico R; Unit of Statistical and Methodological Support to Clinical Research, Azienda Ospedaliero-Universitaria, Modena 41121, Italy.; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena 41124, Italy., Poletti A; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Università degli Studi di Milano, Milan 20122, Italy.; Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Milan 20122, Italy., Mandrioli J; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41121, Italy.; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena 41126, Italy. |
| Corporate Authors: | Co-ALS Investigators Group |
| Source: | Brain communications [Brain Commun] 2024 Sep 05; Vol. 6 (5), pp. fcae304. Date of Electronic Publication: 2024 Sep 05 (Print Publication: 2024). |
| Publication Type: | Clinical Trial; Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2632-1297 |
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| DOI: | 10.1093/braincomms/fcae304 |
