Analysis of genomic alternations in epidermal growth factor receptor (EGFR)-T790M-mutated non-small cell lung cancer (NSCLC) patients with acquired resistance to osimertinib therapy.

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Title: Analysis of genomic alternations in epidermal growth factor receptor (EGFR)-T790M-mutated non-small cell lung cancer (NSCLC) patients with acquired resistance to osimertinib therapy.
Authors: Hsu PC; Division of Thoracic Oncology, Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, 33305, Taiwan.; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Chang JW; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Kwei-Shan, Taoyuan, 33305, Taiwan., Chiu LC; Division of Thoracic Oncology, Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, 33305, Taiwan.; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Yang CT; Division of Thoracic Oncology, Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, 33305, Taiwan.; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.; Department of Internal Medicine, Taoyuan Chang Gung Memorial Hospital, Taoyuan, 33378, Taiwan.; Department of Respiratory Therapy, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Kuo SC; Division of Thoracic Oncology, Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, 33305, Taiwan.; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan., Fang YF; Division of Thoracic Oncology, Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, 33305, Taiwan., Wu CE; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan. jiaoen@gmail.com.; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, 5, Fu-Hsing Street, Kwei-Shan, Taoyuan, 33305, Taiwan. jiaoen@gmail.com.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2025 May; Vol. 27 (5), pp. 1967-1979. Date of Electronic Publication: 2024 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1699-3055
DOI:10.1007/s12094-024-03727-7