Limb Perfusion Delivery of a rAAV1 Alpha-1 Antitrypsin Vector in Non-Human Primates Is Safe but Insufficient for Therapy.
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| Title: | Limb Perfusion Delivery of a rAAV1 Alpha-1 Antitrypsin Vector in Non-Human Primates Is Safe but Insufficient for Therapy. |
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| Authors: | Pires-Ferreira D; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Reil D; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Tang Q; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Blackwood M; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Gallagher T; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Keeler AM; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Pediatrics, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Chichester JA; Gene Therapy Program, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Vyhnal KK; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA., Lindborg JA; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA., Benson J; Lovelace Biomedical Research Institute, Albuquerque, NM 87108, USA., Fu D; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610, USA., Flotte TR; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Pediatrics, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Gruntman AM; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.; Department of Pediatrics, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA. |
| Source: | Genes [Genes (Basel)] 2024 Sep 10; Vol. 15 (9). Date of Electronic Publication: 2024 Sep 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2073-4425 |
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| DOI: | 10.3390/genes15091188 |
