CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.

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Title: CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.
Authors: Sandoval C; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Lee J; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Toth B; Department of Data and Statistical Sciences, Genentech Inc, Immunology, Infectious Diseases and Opthalmology, South San Francisco, California, USA., Nagaraj R; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Schauer SP; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Hoffman J; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA., Calderon E; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA., Kollmorgen G; Roche Diagnostics, GmbH, Penzberg, Germany., Sanabria Bohórquez SM; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Monteiro C; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Teng E; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Hanson JE; Department of Neuroscience, Genentech Inc, South San Francisco, California, USA., Yeh FL; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Gutierrez J; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Biever A; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Nov; Vol. 20 (11), pp. 7940-7953. Date of Electronic Publication: 2024 Oct 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1552-5279
DOI:10.1002/alz.14271