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CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.

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Title: CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.
Authors: Sandoval C; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Lee J; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Toth B; Department of Data and Statistical Sciences, Genentech Inc, Immunology, Infectious Diseases and Opthalmology, South San Francisco, California, USA., Nagaraj R; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Schauer SP; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Hoffman J; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA., Calderon E; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA., Kollmorgen G; Roche Diagnostics, GmbH, Penzberg, Germany., Sanabria Bohórquez SM; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Monteiro C; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Teng E; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA., Hanson JE; Department of Neuroscience, Genentech Inc, South San Francisco, California, USA., Yeh FL; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Gutierrez J; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA., Biever A; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Nov; Vol. 20 (11), pp. 7940-7953. Date of Electronic Publication: 2024 Oct 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.
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  Data: <searchLink fieldCode="AU" term="%22Sandoval+C%22">Sandoval C</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Toth+B%22">Toth B</searchLink>; Department of Data and Statistical Sciences, Genentech Inc, Immunology, Infectious Diseases and Opthalmology, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Nagaraj+R%22">Nagaraj R</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Schauer+SP%22">Schauer SP</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hoffman+J%22">Hoffman J</searchLink>; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Calderon+E%22">Calderon E</searchLink>; Department of Translational Medicine, Genentech Inc, Operations Diagnostics Technology Innovation, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Kollmorgen+G%22">Kollmorgen G</searchLink>; Roche Diagnostics, GmbH, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sanabria+Bohórquez+SM%22">Sanabria Bohórquez SM</searchLink>; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Monteiro+C%22">Monteiro C</searchLink>; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Teng+E%22">Teng E</searchLink>; Department of Early Clinical Development, Genentech Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hanson+JE%22">Hanson JE</searchLink>; Department of Neuroscience, Genentech Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+FL%22">Yeh FL</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+J%22">Gutierrez J</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Biever+A%22">Biever A</searchLink>; Department of Translational Medicine, Genentech Inc, OMNI, South San Francisco, California, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2024 Nov; Vol. 20 (11), pp. 7940-7953. <i>Date of Electronic Publication: </i>2024 Oct 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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        Value: 10.1002/alz.14271
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        Text: English
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              Text: 2024 Nov
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