The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice.
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| Title: | The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice. |
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| Authors: | Wang Q; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre, Auckland, New Zealand., Leask MP; University of Alabama, Birmingham, AL, USA., Lee K; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre, Auckland, New Zealand., Jaiswal J; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Kallingappa P; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Dissanayake W; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre, Auckland, New Zealand., Puli'uvea C; Maurice Wilkins Centre, Auckland, New Zealand.; Department of Biomedicine and Diagnostics, Auckland University of Technology, Auckland, New Zealand., O'Sullivan C; Moko Foundation, Kaitaia, New Zealand., Watson H; Paratene Ngata Research Centre, Ngati Porou Oranga, Te Puia Springs, New Zealand., Wilcox P; Maurice Wilkins Centre, Auckland, New Zealand.; Department of Statistics, University of Otago, Dunedin, New Zealand., Murphy R; Maurice Wilkins Centre, Auckland, New Zealand.; Department of Medicine, University of Auckland, Auckland, New Zealand.; Auckland Diabetes Centre, Te Whatu Ora Health New Zealand, Te Toka Tumai, New Zealand., Merry TL; Maurice Wilkins Centre, Auckland, New Zealand.; Department of Nutrition, University of Auckland, Auckland, New Zealand., Shepherd PR; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand. peter.shepherd@auckland.ac.nz.; Maurice Wilkins Centre, Auckland, New Zealand. peter.shepherd@auckland.ac.nz.; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand. peter.shepherd@auckland.ac.nz. |
| Source: | Diabetologia [Diabetologia] 2025 Mar; Vol. 68 (3), pp. 537-548. Date of Electronic Publication: 2024 Oct 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0428 |
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| DOI: | 10.1007/s00125-024-06287-1 |
