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Depletion of loss-of-function germline mutations in centenarians reveals longevity genes.

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Title: Depletion of loss-of-function germline mutations in centenarians reveals longevity genes.
Authors: Ying K; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; T. H. Chan School of Public Health, Harvard University, Boston, USA., Castro JP; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto and Aging and Aneuploidy Laboratory, IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal., Shindyapina AV; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; Retro Biosciences, Redwood City, USA., Tyshkovskiy A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA., Moqri M; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA., Goeminne LJE; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA., Milman S; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, USA., Zhang ZD; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA., Barzilai N; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, USA., Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA. vgladyshev@rics.bwh.harvard.edu.
Source: Nature communications [Nat Commun] 2024 Oct 19; Vol. 15 (1), pp. 9030. Date of Electronic Publication: 2024 Oct 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Depletion of loss-of-function germline mutations in centenarians reveals longevity genes.
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  Data: <searchLink fieldCode="AU" term="%22Ying+K%22">Ying K</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; T. H. Chan School of Public Health, Harvard University, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Castro+JP%22">Castro JP</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto and Aging and Aneuploidy Laboratory, IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Shindyapina+AV%22">Shindyapina AV</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.; Retro Biosciences, Redwood City, USA.<br /><searchLink fieldCode="AU" term="%22Tyshkovskiy+A%22">Tyshkovskiy A</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Moqri+M%22">Moqri M</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Goeminne+LJE%22">Goeminne LJE</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Milman+S%22">Milman S</searchLink>; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+ZD%22">Zhang ZD</searchLink>; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.<br /><searchLink fieldCode="AU" term="%22Barzilai+N%22">Barzilai N</searchLink>; Department of Genetics, Albert Einstein College of Medicine, Bronx, USA.; Department of Medicine, Albert Einstein College of Medicine, Bronx, USA.<br /><searchLink fieldCode="AU" term="%22Gladyshev+VN%22">Gladyshev VN</searchLink>; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA. vgladyshev@rics.bwh.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Oct 19; Vol. 15 (1), pp. 9030. <i>Date of Electronic Publication: </i>2024 Oct 19.
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              Text: 2024 Oct 19
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