Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice.

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Title: Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice.
Authors: Dos Santos C; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Cambraia A; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Shrestha S; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Cutler M; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Cottam M; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Perkins G; National Center for Imaging and Microscopy Research, University of California San Diego, La Jolla, CA, USA., Lev-Ram V; National Center for Imaging and Microscopy Research, University of California San Diego, La Jolla, CA, USA., Roy B; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Acree C; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Kim KY; National Center for Imaging and Microscopy Research, University of California San Diego, La Jolla, CA, USA., Deerinck T; National Center for Imaging and Microscopy Research, University of California San Diego, La Jolla, CA, USA., Dean D; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., Cartailler JP; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA., MacDonald PE; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Hetzer M; Institute of Science and Technology Austria (ISTA), Vienna, Austria., Ellisman M; National Center for Imaging and Microscopy Research, University of California San Diego, La Jolla, CA, USA., Arrojo E Drigo R; Vanderbilt University, Department of Molecular Physiology and Biophysics, Nashville, La Jolla, TN, USA. r.drigo@vanderbilt.edu.
Source: Nature communications [Nat Commun] 2024 Oct 21; Vol. 15 (1), pp. 9063. Date of Electronic Publication: 2024 Oct 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-53127-2