Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway.

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Title: Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway.
Authors: Gong T; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. tinggong@pitt.edu.; Department of Anesthesiology, Shenzhen Hospital of Southern Medical University, Shenzhen, 518110, Guangdong, China. tinggong@pitt.edu., Wang QD; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Loughran PA; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Li YH; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Scott MJ; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA., Billiar TR; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA., Liu YT; Department of Anesthesiology, Shenzhen Hospital of Southern Medical University, Shenzhen, 518110, Guangdong, China. youtanliuhao@163.com., Fan J; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. jif7@pitt.edu.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, 15219, USA. jif7@pitt.edu.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. jif7@pitt.edu.; Research and Development, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, 15240, USA. jif7@pitt.edu.
Source: Military Medical Research [Mil Med Res] 2024 Oct 28; Vol. 11 (1), pp. 71. Date of Electronic Publication: 2024 Oct 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101643181 Publication Model: Electronic Cited Medium: Internet ISSN: 2054-9369 (Electronic) Linking ISSN: 20549369 NLM ISO Abbreviation: Mil Med Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2054-9369
DOI:10.1186/s40779-024-00574-z