Two cooperative lipid binding sites within the pleckstrin homology domain are necessary for AKT binding and stabilization to the plasma membrane.

Saved in:
Bibliographic Details
Title: Two cooperative lipid binding sites within the pleckstrin homology domain are necessary for AKT binding and stabilization to the plasma membrane.
Authors: Soteriou C; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK; Molecular and Nanoscale Physics Group, School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, UK; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Xu M; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK., Connell SD; Molecular and Nanoscale Physics Group, School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, UK; Astbury Center for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK., Tyler AII; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK., Kalli AC; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK; Astbury Center for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK. Electronic address: a.kalli@leeds.ac.uk., Thorne JL; School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK. Electronic address: j.l.thorne@leeds.ac.uk.
Source: Structure (London, England : 1993) [Structure] 2025 Jan 02; Vol. 33 (1), pp. 181-195.e5. Date of Electronic Publication: 2024 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-4186
DOI:10.1016/j.str.2024.10.020