Generating and validating renewable affimer protein binding reagents targeting SH2 domains.

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Title: Generating and validating renewable affimer protein binding reagents targeting SH2 domains.
Authors: Heseltine SJ; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Billenness GJ; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Martin HL; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Tiede C; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK.; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, UK., Tang AAS; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK.; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, UK., Foy E; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Reddy G; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Gibson N; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK., Johnson M; Avacta Life Sciences, Wetherby, UK., Webb ME; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, UK.; School of Chemistry, University of Leeds, Leeds, UK., McPherson MJ; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK.; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, UK., Tomlinson DC; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK. d.c.tomlinson@leeds.ac.uk.; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, UK. d.c.tomlinson@leeds.ac.uk.
Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28322. Date of Electronic Publication: 2024 Nov 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-024-79357-4