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Oxaliplatin and 5-fluorouracil promote epithelial-mesenchymal transition via activation of KRAS/ERK/NF-κB pathway in KRAS-mutated colon cancer cells.

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Title: Oxaliplatin and 5-fluorouracil promote epithelial-mesenchymal transition via activation of KRAS/ERK/NF-κB pathway in KRAS-mutated colon cancer cells.
Authors: Hoshida T; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.; Department of Pharmacy, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Wakayama, Japan., Tsubaki M; Laboratory of Pharmacotherapy, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Shido, Sanuki, Kagawa, 769-2193, Japan., Takeda T; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Asano R; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Choi IH; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Takimoto K; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Inukai A; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Imano M; Department of Surgery, Kindai University School of Medicine, Osakasayama, Osaka, 589-8511, Japan., Tanabe K; Department of Pharmacy, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Wakayama, Japan., Nagai N; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan., Nishida S; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan. nishida@phar.kindai.ac.jp.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 May; Vol. 480 (5), pp. 2985-2999. Date of Electronic Publication: 2024 Nov 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oxaliplatin and 5-fluorouracil promote epithelial-mesenchymal transition via activation of KRAS/ERK/NF-κB pathway in KRAS-mutated colon cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Hoshida+T%22">Hoshida T</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.; Department of Pharmacy, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tsubaki+M%22">Tsubaki M</searchLink>; Laboratory of Pharmacotherapy, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Shido, Sanuki, Kagawa, 769-2193, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+T%22">Takeda T</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Asano+R%22">Asano R</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Choi+IH%22">Choi IH</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Takimoto+K%22">Takimoto K</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Inukai+A%22">Inukai A</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Imano+M%22">Imano M</searchLink>; Department of Surgery, Kindai University School of Medicine, Osakasayama, Osaka, 589-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Tanabe+K%22">Tanabe K</searchLink>; Department of Pharmacy, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Nagai+N%22">Nagai N</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+S%22">Nishida S</searchLink>; Kindai University Faculty of Pharmacy, Kowakae, Higashiosaka, Osaka, 577-8502, Japan. nishida@phar.kindai.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%220364456%22">Molecular and cellular biochemistry</searchLink> [Mol Cell Biochem] 2025 May; Vol. 480 (5), pp. 2985-2999. <i>Date of Electronic Publication: </i>2024 Nov 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0364456 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-4919 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203008177%22">03008177 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell Biochem <i>Subsets: </i>MEDLINE
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