Xenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy.
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| Title: | Xenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy. |
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| Authors: | Park S; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea., Kwon O; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Lee H; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea., Cho Y; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea., Yeun J; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea., Yoon SH; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea., Sun SY; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea., Huh Y; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Yu WD; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Park S; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Son N; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Jeon S; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Lee S; Digital Biotech Innovation Center, KRIBB, Daejeon, Republic of Korea., Kim DS; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Digital Biotech Innovation Center, KRIBB, Daejeon, Republic of Korea., Lee SY; Nanobio Measurement Group, Division of Biomedical Metrology, Korea Research Institute of Standards and Science (KRISS), 267 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea., Son JG; Nanobio Measurement Group, Division of Biomedical Metrology, Korea Research Institute of Standards and Science (KRISS), 267 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea., Lee KJ; R&D Institute, ORGANOIDSCIENCES Ltd., Seongnam, Republic of Korea., Kim YI; R&D Institute, ORGANOIDSCIENCES Ltd., Seongnam, Republic of Korea., Lim JH; Department of Surgery, Gangnam Severance Hospital, Pancreatobiliary Cancer Clinic, Yonsei University College of Medicine, Seoul, Republic of Korea., Yoo J; R&D Institute, ORGANOIDSCIENCES Ltd., Seongnam, Republic of Korea.; Organoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.; CHA Organoid Research Center, CHA University, Seongnam, Republic of Korea., Lee TG; Nanobio Measurement Group, Division of Biomedical Metrology, Korea Research Institute of Standards and Science (KRISS), 267 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea., Son MY; Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, Republic of Korea. myson@kribb.re.kr.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of Korea. myson@kribb.re.kr.; Organoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea. myson@kribb.re.kr.; School of Medicine, Sungkyunkwan University, Suwon, Republic of Korea. myson@kribb.re.kr., Im SG; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea. sgim@kaist.ac.kr.; KAIST Stem Cell Center, Department of Chemical and Biomolecular Engineering, Graduate School of Stem Cell & Regenerative Biology, KAIST, Daejeon, Republic of Korea. sgim@kaist.ac.kr. |
| Source: | Nature communications [Nat Commun] 2024 Dec 02; Vol. 15 (1), pp. 10492. Date of Electronic Publication: 2024 Dec 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-54653-9 |
