TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate.
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| Title: | TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate. |
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| Authors: | Meng MY; Department of Pharmacology, University of Cambridge, Cambridge, UK., Paine LW; Department of Pharmacology, University of Cambridge, Cambridge, UK., Sagnat D; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France., Bello I; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy., Oldroyd S; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK., Javid F; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK., Harper MT; Department of Pharmacology, University of Cambridge, Cambridge, UK., Hockley JRF; Department of Pharmacology, University of Cambridge, Cambridge, UK., St John Smith E; Department of Pharmacology, University of Cambridge, Cambridge, UK., Owens RM; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK., Alric L; Internal Medicine Department of Digestive Disease, CHU Toulouse-Rangueil and Université de Toulouse, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France., Buscail E; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.; Department of Surgery, CHU Toulouse-Rangueil and Université de Toulouse, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France., Welsh F; BioPharmaceuticals R&D, AstraZeneca, Neuroscience, Cambridge, UK., Vergnolle N; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.; Department of Physiology and Pharmacology, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada., Bulmer DC; Department of Pharmacology, University of Cambridge, Cambridge, UK. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2025 Mar; Vol. 182 (6), pp. 1324-1340. Date of Electronic Publication: 2024 Dec 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-5381 |
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| DOI: | 10.1111/bph.17408 |
