Blood-based biomarkers for early frailty are sex-specific: validation of a combined in silico prediction and data-driven approach.
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| Title: | Blood-based biomarkers for early frailty are sex-specific: validation of a combined in silico prediction and data-driven approach. |
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| Authors: | de Jong JCBC; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands. j.dejong@tno.nl.; Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands. j.dejong@tno.nl.; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands. j.dejong@tno.nl., Caspers MPM; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Dulos R; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Snabel J; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., van der Hoek MD; Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands.; Applied Research Centre Food and Dairy, Van Hall Larenstein University of Applied Sciences, Leeuwarden, The Netherlands.; MCL Academy, Medical Centre Leeuwarden, Leeuwarden, The Netherlands., van der Leij FR; Applied Research Centre Food and Dairy, Van Hall Larenstein University of Applied Sciences, Leeuwarden, The Netherlands.; RIC-AFL Inholland University of Applied Sciences, Delft and Amsterdam, The Netherlands., Kleemann R; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Keijer J; Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands., Nieuwenhuizen AG; Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands., van den Hoek AM; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Verschuren L; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands. |
| Source: | GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 3741-3758. Date of Electronic Publication: 2024 Dec 03. |
| Publication Type: | Journal Article; Validation Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2509-2723 |
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| DOI: | 10.1007/s11357-024-01449-w |
