Autoantibody profiles in Alzheimer´s, Parkinson´s, and dementia with Lewy bodies: altered IgG affinity and IgG/IgM/IgA responses to alpha-synuclein, amyloid-beta, and tau in disease-specific pathological patterns.

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Title: Autoantibody profiles in Alzheimer´s, Parkinson´s, and dementia with Lewy bodies: altered IgG affinity and IgG/IgM/IgA responses to alpha-synuclein, amyloid-beta, and tau in disease-specific pathological patterns.
Authors: Knecht L; Centre for Neuroscience and Stereology, Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 6B, Entrance 11B, 2. floor, Copenhagen, NV, DK-2400, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 4B, Copenhagen, NV, DK-2400, Denmark., Dalsbøl K; Centre for Neuroscience and Stereology, Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 6B, Entrance 11B, 2. floor, Copenhagen, NV, DK-2400, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 4B, Copenhagen, NV, DK-2400, Denmark., Simonsen AH; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark., Pilchner F; Chair of Geriatric Medicine, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, Hufelandstraße 55, DE-45147, Essen, Germany., Ross JA; Chair of Geriatric Medicine, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, Hufelandstraße 55, DE-45147, Essen, Germany., Winge K; Odense University Hospital, University of Southern Denmark, Copenhagen, Denmark., Salvesen L; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 7, Copenhagen, NV, DK-2400, Denmark., Bech S; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 7, Copenhagen, NV, DK-2400, Denmark., Hejl AM; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 7, Copenhagen, NV, DK-2400, Denmark., Løkkegaard A; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 7, Copenhagen, NV, DK-2400, Denmark., Hasselbalch SG; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen Ø, DK-2100, Denmark., Dodel R; Chair of Geriatric Medicine, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, Hufelandstraße 55, DE-45147, Essen, Germany., Aznar S; Centre for Neuroscience and Stereology, Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 6B, Entrance 11B, 2. floor, Copenhagen, NV, DK-2400, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 4B, Copenhagen, NV, DK-2400, Denmark., Waldemar G; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen Ø, DK-2100, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen Ø, DK-2100, Denmark., Brudek T; Centre for Neuroscience and Stereology, Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 6B, Entrance 11B, 2. floor, Copenhagen, NV, DK-2400, Denmark. Tomasz.Brudek@regionh.dk.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 4B, Copenhagen, NV, DK-2400, Denmark. Tomasz.Brudek@regionh.dk., Folke J; Centre for Neuroscience and Stereology, Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 6B, Entrance 11B, 2. floor, Copenhagen, NV, DK-2400, Denmark. Jonas.folke@regionh.dk.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Nielsine Nielsens Vej 4B, Copenhagen, NV, DK-2400, Denmark. Jonas.folke@regionh.dk.; Chair of Geriatric Medicine, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, Hufelandstraße 55, DE-45147, Essen, Germany. Jonas.folke@regionh.dk.
Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Dec 03; Vol. 21 (1), pp. 317. Date of Electronic Publication: 2024 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1742-2094
DOI:10.1186/s12974-024-03293-3