View in EDS HTML Full Text PDF Full Text

Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.

Saved in:
Bibliographic Details
Title: Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Authors: Dinkel L; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Hummel S; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Zenatti V; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Malara M; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Tillmann Y; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Colombo A; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Monasor LS; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Suh JH; Denali Therapeutics Inc., South San Francisco, CA 94080, USA., Logan T; Denali Therapeutics Inc., South San Francisco, CA 94080, USA., Roth S; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Paeger L; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Hoffelner P; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, 82152 Planegg-Martinsried, Germany., Bludau O; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany., Schmidt A; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, 82152 Planegg-Martinsried, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany., Schifferer M; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Nuscher B; Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 81377 Munich, Germany., Njavro JR; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Prestel M; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany., Bartos LM; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Wind-Mark K; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Slemann L; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Hoermann L; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Kunte ST; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Gnörich J; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Lindner S; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Simons M; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Institute of Neuronal Cell Biology (TUM-NZB), Technical University of Munich, 80802 Munich, Germany., Herms J; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Center for Neuropathology and Prion Research, Ludwig-Maximilians-University München, 81377 Munich, Germany., Paquet D; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Bartenstein P; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Franzmeier N; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Department of Psychiatry and Neurochemistry, University of Gothenburg, Sahlgrenska Academy, Institute of Neuroscience and Physiology, SE-413 90 Mölndal and Gothenburg, Sweden., Liesz A; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Grosche A; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany., Bremova-Ertl T; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Department of Neurology, University Hospital Bern, 3010 Bern, Switzerland., Catarino C; Friedrich Baur Institute, Department of Neurology, LMU University Hospital, LMU Munich, 80336 Munich, Germany., Beblo S; Center for Pediatric Research Leipzig, Department of Women and Child Health, Hospital for Children and Adolescents, University Hospital Leipzig; Leipzig University Center for Rare Diseases, 04103 Leipzig, Germany., Bergner C; Department of Neurology, University Hospital Leipzig, 04103 Leipzig, Germany., Schneider SA; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Strupp M; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Di Paolo G; Denali Therapeutics Inc., South San Francisco, CA 94080, USA., Brendel M; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Tahirovic S; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
Source: Science translational medicine [Sci Transl Med] 2024 Dec 04; Vol. 16 (776), pp. eadl4616. Date of Electronic Publication: 2024 Dec 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39630885
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dinkel+L%22">Dinkel L</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hummel+S%22">Hummel S</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zenatti+V%22">Zenatti V</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Malara+M%22">Malara M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tillmann+Y%22">Tillmann Y</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Colombo+A%22">Colombo A</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Monasor+LS%22">Monasor LS</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Suh+JH%22">Suh JH</searchLink>; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Logan+T%22">Logan T</searchLink>; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Roth+S%22">Roth S</searchLink>; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Paeger+L%22">Paeger L</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffelner+P%22">Hoffelner P</searchLink>; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, 82152 Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Bludau+O%22">Bludau O</searchLink>; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+A%22">Schmidt A</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Graduate School of Systemic Neurosciences, Ludwig Maximilian University, 82152 Planegg-Martinsried, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+SA%22">Müller SA</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schifferer+M%22">Schifferer M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Nuscher+B%22">Nuscher B</searchLink>; Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Njavro+JR%22">Njavro JR</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Prestel+M%22">Prestel M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bartos+LM%22">Bartos LM</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wind-Mark+K%22">Wind-Mark K</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Slemann+L%22">Slemann L</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoermann+L%22">Hoermann L</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kunte+ST%22">Kunte ST</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gnörich+J%22">Gnörich J</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lindner+S%22">Lindner S</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Simons+M%22">Simons M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Institute of Neuronal Cell Biology (TUM-NZB), Technical University of Munich, 80802 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Herms+J%22">Herms J</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Center for Neuropathology and Prion Research, Ludwig-Maximilians-University München, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Paquet+D%22">Paquet D</searchLink>; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lichtenthaler+SF%22">Lichtenthaler SF</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Neuroproteomics School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bartenstein+P%22">Bartenstein P</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Franzmeier+N%22">Franzmeier N</searchLink>; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Department of Psychiatry and Neurochemistry, University of Gothenburg, Sahlgrenska Academy, Institute of Neuroscience and Physiology, SE-413 90 Mölndal and Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Liesz+A%22">Liesz A</searchLink>; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Grosche+A%22">Grosche A</searchLink>; Department of Physiological Genomics, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Bremova-Ertl+T%22">Bremova-Ertl T</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Department of Neurology, University Hospital Bern, 3010 Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Catarino+C%22">Catarino C</searchLink>; Friedrich Baur Institute, Department of Neurology, LMU University Hospital, LMU Munich, 80336 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Beblo+S%22">Beblo S</searchLink>; Center for Pediatric Research Leipzig, Department of Women and Child Health, Hospital for Children and Adolescents, University Hospital Leipzig; Leipzig University Center for Rare Diseases, 04103 Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Bergner+C%22">Bergner C</searchLink>; Department of Neurology, University Hospital Leipzig, 04103 Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+SA%22">Schneider SA</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Strupp+M%22">Strupp M</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Di+Paolo+G%22">Di Paolo G</searchLink>; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Brendel+M%22">Brendel M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tahirovic+S%22">Tahirovic S</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2024 Dec 04; Vol. 16 (776), pp. eadl4616. <i>Date of Electronic Publication: </i>2024 Dec 04.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39630885
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/scitranslmed.adl4616
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eadl4616
    Titles:
      – TitleFull: Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dinkel L
      – PersonEntity:
          Name:
            NameFull: Hummel S
      – PersonEntity:
          Name:
            NameFull: Zenatti V
      – PersonEntity:
          Name:
            NameFull: Malara M
      – PersonEntity:
          Name:
            NameFull: Tillmann Y
      – PersonEntity:
          Name:
            NameFull: Colombo A
      – PersonEntity:
          Name:
            NameFull: Monasor LS
      – PersonEntity:
          Name:
            NameFull: Suh JH
      – PersonEntity:
          Name:
            NameFull: Logan T
      – PersonEntity:
          Name:
            NameFull: Roth S
      – PersonEntity:
          Name:
            NameFull: Paeger L
      – PersonEntity:
          Name:
            NameFull: Hoffelner P
      – PersonEntity:
          Name:
            NameFull: Bludau O
      – PersonEntity:
          Name:
            NameFull: Schmidt A
      – PersonEntity:
          Name:
            NameFull: Müller SA
      – PersonEntity:
          Name:
            NameFull: Schifferer M
      – PersonEntity:
          Name:
            NameFull: Nuscher B
      – PersonEntity:
          Name:
            NameFull: Njavro JR
      – PersonEntity:
          Name:
            NameFull: Prestel M
      – PersonEntity:
          Name:
            NameFull: Bartos LM
      – PersonEntity:
          Name:
            NameFull: Wind-Mark K
      – PersonEntity:
          Name:
            NameFull: Slemann L
      – PersonEntity:
          Name:
            NameFull: Hoermann L
      – PersonEntity:
          Name:
            NameFull: Kunte ST
      – PersonEntity:
          Name:
            NameFull: Gnörich J
      – PersonEntity:
          Name:
            NameFull: Lindner S
      – PersonEntity:
          Name:
            NameFull: Simons M
      – PersonEntity:
          Name:
            NameFull: Herms J
      – PersonEntity:
          Name:
            NameFull: Paquet D
      – PersonEntity:
          Name:
            NameFull: Lichtenthaler SF
      – PersonEntity:
          Name:
            NameFull: Bartenstein P
      – PersonEntity:
          Name:
            NameFull: Franzmeier N
      – PersonEntity:
          Name:
            NameFull: Liesz A
      – PersonEntity:
          Name:
            NameFull: Grosche A
      – PersonEntity:
          Name:
            NameFull: Bremova-Ertl T
      – PersonEntity:
          Name:
            NameFull: Catarino C
      – PersonEntity:
          Name:
            NameFull: Beblo S
      – PersonEntity:
          Name:
            NameFull: Bergner C
      – PersonEntity:
          Name:
            NameFull: Schneider SA
      – PersonEntity:
          Name:
            NameFull: Strupp M
      – PersonEntity:
          Name:
            NameFull: Di Paolo G
      – PersonEntity:
          Name:
            NameFull: Brendel M
      – PersonEntity:
          Name:
            NameFull: Tahirovic S
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 04
              M: 12
              Text: 2024 Dec 04
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 776
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1