Impact of administration routes and dose frequency on the toxicology of SARS-CoV-2 mRNA vaccines in mice model.

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Title: Impact of administration routes and dose frequency on the toxicology of SARS-CoV-2 mRNA vaccines in mice model.
Authors: Ahn JH; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Lee J; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Republic of Korea., Roh G; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Republic of Korea.; BK Four Department of Biotechnology, The Catholic University of Korea, Bucheon, Republic of Korea., Lee NY; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea., Bae HJ; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon E; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Han KM; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Pathology, CHA Ilsan Medical Center, CHA University, Goyang-si, Republic of Korea., Kim JE; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Park HJ; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Republic of Korea.; BK Four Department of Biotechnology, The Catholic University of Korea, Bucheon, Republic of Korea., Yoo S; Center for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea., Kwon SP; Center for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea., Bang EK; Center for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea., Keum G; Center for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea., Nam JH; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Republic of Korea. jhnam@catholic.ac.kr.; BK Four Department of Biotechnology, The Catholic University of Korea, Bucheon, Republic of Korea. jhnam@catholic.ac.kr., Kang BC; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea. bckang@snu.ac.kr.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. bckang@snu.ac.kr.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea. bckang@snu.ac.kr.
Source: Archives of toxicology [Arch Toxicol] 2025 Feb; Vol. 99 (2), pp. 755-773. Date of Electronic Publication: 2024 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0738
DOI:10.1007/s00204-024-03912-1