Acquired resistance to PD-L1 inhibition enhances a type I IFN-regulated secretory program in tumors.
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| Title: | Acquired resistance to PD-L1 inhibition enhances a type I IFN-regulated secretory program in tumors. |
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| Authors: | Shi Y; Department of Experimental Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., McKenery A; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Dolan M; Department of Experimental Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Mastri M; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Hill JW; Jacobs School of Medicine and Biomedical Sciences, SUNY at Buffalo, Buffalo, USA., Dommer A; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Benzekry S; Computational Pharmacology and Clinical Oncology (COMPO), Inria Sophia Antipolis-Méditerranée, Centre de Recherches en Cancérologie de Marseille, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Faculté de Pharmacie, Aix-Marseille University, Marseille, France., Long M; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Puzanov I; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Ebos JML; Department of Experimental Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA. John.Ebos@RoswellPark.org.; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA. John.Ebos@RoswellPark.org.; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA. John.Ebos@RoswellPark.org. |
| Source: | EMBO reports [EMBO Rep] 2025 Jan; Vol. 26 (2), pp. 521-559. Date of Electronic Publication: 2024 Dec 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.1038/s44319-024-00333-0 |