Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892).
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| Title: | Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892). |
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| Authors: | Taylor SE; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. taylorse2@upmc.edu.; Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. taylorse2@upmc.edu., Behr S; Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cooper KL; Biostatistics Facility, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Mahdi H; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Cancer Immunology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Fabian D; Markey Cancer Center, Lexington, KY, USA., Gallion H; Markey Cancer Center, Lexington, KY, USA., Ueland F; Markey Cancer Center, Lexington, KY, USA., Vargo J; Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Orr B; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Girda E; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Courtney-Brooks M; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Olawaiye AB; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Randall LM; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology and Massey Comprehensive Cancer Center, Virginia Commonwealth University Health, Richmond, VA, USA., Richardson DL; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Sullivan SA; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology and Massey Comprehensive Cancer Center, Virginia Commonwealth University Health, Richmond, VA, USA., Huang M; Division of Gynecologic Oncology, University of Virginia, Charlottesville, VA, USA., Christner SM; Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Beriwal S; Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Lin Y; Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Biostatistics Facility, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Chauhan A; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Chu E; Montefiore Einstein Cancer Canter, Bronx, NY, USA., Kohn EC; Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA., Kunos C; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Ivy SP; Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA., Beumer JH; Cancer Therapeutics Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. beumerj@gmail.com.; Department of Pharmaceutical Sciences, School of Pharmacy, Pittsburgh, PA, USA. beumerj@gmail.com.; Division of Hematology/Oncology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. beumerj@gmail.com. |
| Source: | Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Dec 14; Vol. 95 (1), pp. 4. Date of Electronic Publication: 2024 Dec 14. |
| Publication Type: | Journal Article; Clinical Trial, Phase I |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0843 |
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| DOI: | 10.1007/s00280-024-04720-1 |
