Epoxy metabolites of linoleic acid promote the development of breast cancer via orchestrating PLEC/NFκB1/CXCL9-mediated tumor growth and metastasis.

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Title: Epoxy metabolites of linoleic acid promote the development of breast cancer via orchestrating PLEC/NFκB1/CXCL9-mediated tumor growth and metastasis.
Authors: Ni KD; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Fu X; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Luo Y; Department of Clinical Laboratory, Shanghai Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China., He X; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Yin HH; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Mo DP; Department of Clinical Laboratory, Jiangsu Cancer Hospital, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Institute of Cancer Research, Nanjing, China., Wu JX; Department of Pathology, College of Basic Medicine of Chongqing Medical University, Chongqing, China.; Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, Chongqing, China.; Department of Pathology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wu MJ; Center for Science & technology Innovation, Chongqing Medical University, Chongqing, China., Zheng X; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China.; Center for Novel Target and Therapeutic Intervention (CNTTI), College of Pharmacy, Chongqing Medical University, Chongqing, China., Liu YN; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Jiang Q; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Zhang LT; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Lin AZ; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Huang L; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Pan QJ; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China.; Center for Novel Target and Therapeutic Intervention (CNTTI), College of Pharmacy, Chongqing Medical University, Chongqing, China., Yin XD; The Department of Breast and Thyroid surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Zhang HY; The Second Clinical College of Chongqing Medical University, Chongqing, China., Meng YW; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Zhou X; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China., Pan J; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China.; Center for Novel Target and Therapeutic Intervention (CNTTI), College of Pharmacy, Chongqing Medical University, Chongqing, China., Guo Z; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China.; Center for Novel Target and Therapeutic Intervention (CNTTI), College of Pharmacy, Chongqing Medical University, Chongqing, China., Liu JY; CNTTI of College of Pharmacy and Department of Anesthesia of the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. jyliu@cqmu.edu.cn.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing, China. jyliu@cqmu.edu.cn.; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Chongqing Medical University, Chongqing, China. jyliu@cqmu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2024 Dec 18; Vol. 15 (12), pp. 901. Date of Electronic Publication: 2024 Dec 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-024-07300-6