Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma.

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Title: Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma.
Authors: Oshikiri H; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Taguchi K; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Hirose W; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Taniyama Y; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Kamei T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Siegel D; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ross D; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Kitson RRA; Department of Organic and Bioorganic Chemistry, Charles University, Hradec Králové, Czech Republic., Baird L; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Yamamoto M; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Source: Molecular and cellular biology [Mol Cell Biol] 2025; Vol. 45 (2), pp. 79-97. Date of Electronic Publication: 2024 Dec 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1098-5549
DOI:10.1080/10985549.2024.2438817