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Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma.

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Title: Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma.
Authors: Oshikiri H; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Taguchi K; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Hirose W; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Taniyama Y; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Kamei T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan., Siegel D; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ross D; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Kitson RRA; Department of Organic and Bioorganic Chemistry, Charles University, Hradec Králové, Czech Republic., Baird L; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Yamamoto M; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Source: Molecular and cellular biology [Mol Cell Biol] 2025; Vol. 45 (2), pp. 79-97. Date of Electronic Publication: 2024 Dec 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Oshikiri+H%22">Oshikiri H</searchLink>; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Taguchi+K%22">Taguchi K</searchLink>; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Hirose+W%22">Hirose W</searchLink>; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Taniyama+Y%22">Taniyama Y</searchLink>; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Kamei+T%22">Kamei T</searchLink>; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Siegel+D%22">Siegel D</searchLink>; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ross+D%22">Ross D</searchLink>; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Kitson+RRA%22">Kitson RRA</searchLink>; Department of Organic and Bioorganic Chemistry, Charles University, Hradec Králové, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Baird+L%22">Baird L</searchLink>; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
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  Data: <searchLink fieldCode="JN" term="%228109087%22">Molecular and cellular biology</searchLink> [Mol Cell Biol] 2025; Vol. 45 (2), pp. 79-97. <i>Date of Electronic Publication: </i>2024 Dec 24.
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