GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study.

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Title: GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study.
Authors: Magavern EF; Centre of Clinical Pharmacology & Precision Medicine, William Harvey Research Institute, Queen Mary University of London, London, UK; NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, UK., Deshmukh H; Mackay Base Hospital, Queensland Health, Queensland, Australia., Asselin G; Faculty of Medicine, Université de Montréal, and the Montreal Heart Institute, Montreal, Canada., Theusch E; Department of Pediatrics, University of California San Francisco, Oakland, CA, United States., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Li X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Seeman TE; Division of Geriatrics, Dept of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Tardif JC; Faculty of Medicine, Université de Montréal, and the Montreal Heart Institute, Montreal, Canada., Paul DS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK; Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Cambridge, UK., Benjamin EJ; Boston University Chobanian & Avedisian School of Medicine and School of Public Health, NHLBI and Boston University's Framingham Heart Study, Framingham, MA, United States., Heard-Costa NL; Boston University Chobanian & Avedisian School of Medicine and School of Public Health, NHLBI and Boston University's Framingham Heart Study, Framingham, MA, United States., Vasan RS; Boston University Chobanian & Avedisian School of Medicine and School of Public Health, NHLBI and Boston University's Framingham Heart Study, Framingham, MA, United States., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Krauss RM; Department of Pediatrics, University of California San Francisco, Oakland, CA, United States., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA, United States., Munroe PB; Centre of Clinical Pharmacology & Precision Medicine, William Harvey Research Institute, Queen Mary University of London, London, UK; NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, UK., Caulfield MJ; Centre of Clinical Pharmacology & Precision Medicine, William Harvey Research Institute, Queen Mary University of London, London, UK; NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA, United States., Dubé MP; Faculty of Medicine, Université de Montréal, and the Montreal Heart Institute, Montreal, Canada., Hitman GA; Centre of Genomic Medicine and Child Health, Blizard Institute, Queen Mary University of London, London, UK., Warren HR; Centre of Clinical Pharmacology & Precision Medicine, William Harvey Research Institute, Queen Mary University of London, London, UK; NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, UK. Electronic address: h.r.warren@qmul.ac.uk.
Corporate Authors: Genomic Investigation of Statin Therapy Consortium (GIST)
Source: Pharmacological research [Pharmacol Res] 2025 Feb; Vol. 212, pp. 107575. Date of Electronic Publication: 2025 Jan 09.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-1186
DOI:10.1016/j.phrs.2024.107575