Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration.
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| Title: | Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration. |
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| Authors: | Li LJ; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Liang SY; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Sun XY; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China., Zhu J; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Niu XY; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.; College of Life Science, Ningxia University, Yinchuan, 750021, China., Du XY; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Huang YR; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China. yrhuang@ipe.ac.cn., Liu RT; State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China. rtliu@ipe.ac.cn. |
| Source: | Journal of neuroinflammation [J Neuroinflammation] 2025 Jan 20; Vol. 22 (1), pp. 11. Date of Electronic Publication: 2025 Jan 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1742-2094 |
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| DOI: | 10.1186/s12974-025-03333-6 |
