Antibacterial activities of phytochemical constituents from the leaves of Coula edulis (Olacaceae) and In silico investigations of ursolic acid.

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Title: Antibacterial activities of phytochemical constituents from the leaves of Coula edulis (Olacaceae) and In silico investigations of ursolic acid.
Authors: Kepawou MG; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon.; Drug Discovery and Smart Molecules Research Laboratory, Department of Chemical Sciences, University of Johannesburg, Doornfontein, Johannesburg, South Africa.; Center for Natural Product Research (CNPR), Chemical Sciences Department, University of Johannesburg, Doornfontein, Johannesburg, South Africa., Nguemdjo Chimeze VW; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Kamdem MHK; Drug Discovery and Smart Molecules Research Laboratory, Department of Chemical Sciences, University of Johannesburg, Doornfontein, Johannesburg, South Africa.; Center for Natural Product Research (CNPR), Chemical Sciences Department, University of Johannesburg, Doornfontein, Johannesburg, South Africa.; Research Center for Synthesis and catalysis; Department of Chemical Sciences, University of Johannesburg-Kingsway Campus, Auckland Park, South Africa., Ambamba Akamba BD; Department of Biochemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Melogmo YKD; Department of Biochemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Nkoumou AH; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Wakeu BNK; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Talla RM; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Foudjo Melacheu GL; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Mpho Mmutlane E; Center for Natural Product Research (CNPR), Chemical Sciences Department, University of Johannesburg, Doornfontein, Johannesburg, South Africa., Ndinteh DT; Center for Natural Product Research (CNPR), Chemical Sciences Department, University of Johannesburg, Doornfontein, Johannesburg, South Africa.; Research Center for Synthesis and catalysis; Department of Chemical Sciences, University of Johannesburg-Kingsway Campus, Auckland Park, South Africa., Mbazoa CD; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon., Wandji J; Laboratory of Natural Products and Heterocyclic Synthesis, Department of Organic Chemistry, Faculty of Sciences, The University of Yaoundé 1, Yaoundé, Cameroon.
Source: Natural product research [Nat Prod Res] 2026 Jun; Vol. 40 (11), pp. 3215-3221. Date of Electronic Publication: 2025 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1478-6427
DOI:10.1080/14786419.2025.2458671