Grape Seed Extract Pretreatment Prevents Mitochondrial Dysfunction and NLRP3 Inflammasome-Induced Inflammatory Response in Glial Cells Exposed to Paroxetine and Quinolinic Acid.

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Title: Grape Seed Extract Pretreatment Prevents Mitochondrial Dysfunction and NLRP3 Inflammasome-Induced Inflammatory Response in Glial Cells Exposed to Paroxetine and Quinolinic Acid.
Authors: Rigotti M; Laboratory of Oxidative Stress and Antioxidants, Institute of Biotechnology, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, 95070 560, Brazil., Finger LF; Laboratory of Oxidative Stress and Antioxidants, Institute of Biotechnology, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, 95070 560, Brazil., Scariot FJ; Laboratory of Enology and Applied Microbiology, Institute of Biotechnology, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, Brazil., Machado AK; Cell Culture and Bioactive Effects Laboratory, Universidade Franciscana (UFN), Santa Maria, RS, Brazil., de Avila E Silva S; Laboratory of Computational Biology and Bioinformatics, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, Brazil., Salvador M; Laboratory of Oxidative Stress and Antioxidants, Institute of Biotechnology, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, 95070 560, Brazil., Branco CS; Laboratory of Oxidative Stress and Antioxidants, Institute of Biotechnology, Universidade de Caxias Do Sul (UCS), Caxias Do Sul, RS, 95070 560, Brazil. csbranc1@ucs.br.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Jun; Vol. 62 (6), pp. 7110-7123. Date of Electronic Publication: 2025 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-1182
DOI:10.1007/s12035-025-04730-x