Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways.
Saved in:
| Title: | Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways. |
|---|---|
| Authors: | Moysidou GS; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece., Garantziotis P; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany., Sentis G; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece., Nikoleri D; Laboratory of Auoimmunity-Inflammation, Institute of Molecular Biology and Biotechnology, Heraklion, Greece., Malissovas N; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece., Nikoloudaki M; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece., Stergioti EM; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece., Polia S; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece., Paschalidis N; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece., Filia A; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece., Grigoriou M; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 1st Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace - Alexandropoulis Campus, Alexandroupolis, Greece., Nikolopoulos D; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; Division of Rheumatology, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden., Kapsala N; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece., Katechis S; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University School of Medicine, Athens, Greece., Fanouriakis A; 4th Department of Medicine, National and Kapodistrian University Faculty of Medicine, Athens, Greece., Bertsias G; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece; Laboratory of Autoimmunity-Inflammation, Institute of Molecular Biology and Biotechnology, Heraklion, Greece. Electronic address: https://twitter.com/george_bertsias., Boumpas DT; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece. Electronic address: boumpasd@uoc.gr. |
| Source: | Annals of the rheumatic diseases [Ann Rheum Dis] 2025 Feb; Vol. 84 (2), pp. 262-273. Date of Electronic Publication: 2025 Jan 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39919899 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Moysidou+GS%22">Moysidou GS</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Garantziotis+P%22">Garantziotis P</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Sentis+G%22">Sentis G</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Nikoleri+D%22">Nikoleri D</searchLink>; Laboratory of Auoimmunity-Inflammation, Institute of Molecular Biology and Biotechnology, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Malissovas+N%22">Malissovas N</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Nikoloudaki+M%22">Nikoloudaki M</searchLink>; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Stergioti+EM%22">Stergioti EM</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Polia+S%22">Polia S</searchLink>; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Paschalidis+N%22">Paschalidis N</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Filia+A%22">Filia A</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Grigoriou+M%22">Grigoriou M</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 1st Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace - Alexandropoulis Campus, Alexandroupolis, Greece.<br /><searchLink fieldCode="AU" term="%22Nikolopoulos+D%22">Nikolopoulos D</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; Division of Rheumatology, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kapsala+N%22">Kapsala N</searchLink>; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Katechis+S%22">Katechis S</searchLink>; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Fanouriakis+A%22">Fanouriakis A</searchLink>; 4th Department of Medicine, National and Kapodistrian University Faculty of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Bertsias+G%22">Bertsias G</searchLink>; Rheumatology, Clinical Immunology and Allergy Department, University of Crete School of Medicine, Heraklion, Greece; Laboratory of Autoimmunity-Inflammation, Institute of Molecular Biology and Biotechnology, Heraklion, Greece. Electronic address: https://twitter.com/george&#95;bertsias.<br /><searchLink fieldCode="AU" term="%22Boumpas+DT%22">Boumpas DT</searchLink>; Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy, Athens, Greece; 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University Faculty of Medicine, Athens, Greece. Electronic address: boumpasd@uoc.gr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220372355%22">Annals of the rheumatic diseases</searchLink> [Ann Rheum Dis] 2025 Feb; Vol. 84 (2), pp. 262-273. <i>Date of Electronic Publication: </i>2025 Jan 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372355 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1468-2060 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200034967%22">00034967 </searchLink><i>NLM ISO Abbreviation: </i>Ann Rheum Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39919899 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1136/ard-2024-226051 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 262 Titles: – TitleFull: Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moysidou GS – PersonEntity: Name: NameFull: Garantziotis P – PersonEntity: Name: NameFull: Sentis G – PersonEntity: Name: NameFull: Nikoleri D – PersonEntity: Name: NameFull: Malissovas N – PersonEntity: Name: NameFull: Nikoloudaki M – PersonEntity: Name: NameFull: Stergioti EM – PersonEntity: Name: NameFull: Polia S – PersonEntity: Name: NameFull: Paschalidis N – PersonEntity: Name: NameFull: Filia A – PersonEntity: Name: NameFull: Grigoriou M – PersonEntity: Name: NameFull: Nikolopoulos D – PersonEntity: Name: NameFull: Kapsala N – PersonEntity: Name: NameFull: Katechis S – PersonEntity: Name: NameFull: Fanouriakis A – PersonEntity: Name: NameFull: Bertsias G – PersonEntity: Name: NameFull: Boumpas DT IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2025 Feb Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1468-2060 Numbering: – Type: volume Value: 84 – Type: issue Value: 2 Titles: – TitleFull: Annals of the rheumatic diseases Type: main |
| ResultId | 1 |
