Evaluating predictors of kinase activity of STK11 variants identified in primary human non-small cell lung cancers.

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Title: Evaluating predictors of kinase activity of STK11 variants identified in primary human non-small cell lung cancers.
Authors: Chen Y; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, 98105, USA., Lee K; 3billion, 3billion Biotechnology Company, Seoul, South Korea., Woo J; 3billion, 3billion Biotechnology Company, Seoul, South Korea., Kim DW; 3billion, 3billion Biotechnology Company, Seoul, South Korea., Keum C; 3billion, 3billion Biotechnology Company, Seoul, South Korea., Babbi G; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Casadio R; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Martelli PL; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Savojardo C; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Manfredi M; Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy., Shen Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, 77843, USA., Sun Y; Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, 77843, USA., Katsonis P; Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Lichtarge O; Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Pejaver V; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Seward DJ; Department of Pathology, University of Vermont, Burlington, VT, 5445, USA., Kamandula A; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA., Bakolitsa C; University of California, Berkeley, Berkeley, CA, 94720, USA., Brenner SE; University of California, Berkeley, Berkeley, CA, 94720, USA., Radivojac P; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA., O'Donnell-Luria A; Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Broad Center for Mendelian Genomics, Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA., Mooney SD; Center for Information Technology, National Institutes of Health, Bethesda, MD, 20892, USA. sean.mooney@nih.gov., Jain S; Khoury College of Computer Sciences, Northeastern University, Boston, MA, 02115, USA. sh.jain@northeastern.edu.; The Institute for Experiential AI, Northeastern University, Boston, MA, 02115, USA. sh.jain@northeastern.edu.
Source: Human genetics [Hum Genet] 2025 Mar; Vol. 144 (2-3), pp. 127-142. Date of Electronic Publication: 2025 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1203 (Electronic) Linking ISSN: 03406717 NLM ISO Abbreviation: Hum Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1203
DOI:10.1007/s00439-025-02726-0