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High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.

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Title: High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.
Authors: Gelb T; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Garman KA; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Urban D; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Coxon A; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Gryder B; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Hill NT; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Miao L; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Lee T; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Lee O; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Chakka S; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Braisted J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Jarvis JE; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Glavin R; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Raj TS; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Xiao Y; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Difilippantonio S; Laboratory of Animal Sciences Program, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Wang AQ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Cheng KC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Lal-Nag M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Brownell I; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. isaac.brownell@nih.gov.
Source: Nature communications [Nat Commun] 2025 Feb 12; Vol. 16 (1), pp. 1583. Date of Electronic Publication: 2025 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Gelb+T%22">Gelb T</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Garman+KA%22">Garman KA</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Urban+D%22">Urban D</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Coxon+A%22">Coxon A</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Gryder+B%22">Gryder B</searchLink>; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.<br /><searchLink fieldCode="AU" term="%22Hill+NT%22">Hill NT</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Miao+L%22">Miao L</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Lee+T%22">Lee T</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Lee+O%22">Lee O</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Chakka+S%22">Chakka S</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Braisted+J%22">Braisted J</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Jarvis+JE%22">Jarvis JE</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Glavin+R%22">Glavin R</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Raj+TS%22">Raj TS</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+Y%22">Xiao Y</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Difilippantonio+S%22">Difilippantonio S</searchLink>; Laboratory of Animal Sciences Program, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Wang+AQ%22">Wang AQ</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+KC%22">Cheng KC</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Lal-Nag+M%22">Lal-Nag M</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Hall+MD%22">Hall MD</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Brownell+I%22">Brownell I</searchLink>; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. isaac.brownell@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Feb 12; Vol. 16 (1), pp. 1583. <i>Date of Electronic Publication: </i>2025 Feb 12.
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