Adipose chemokine ligand CX3CL1 contributes to maintaining the hippocampal BDNF level, and the effect is attenuated in advanced age.
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| Title: | Adipose chemokine ligand CX3CL1 contributes to maintaining the hippocampal BDNF level, and the effect is attenuated in advanced age. |
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| Authors: | Takei Y; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo, 143-8540, Japan. yoshinori.takei@med.toho-u.ac.jp.; YOKOYAMA Kazuya Cancer Research Institute, 2F Ueno Yokoyama Bidg, 1-4-8 Ueno, Taito-Ku, Tokyo, 110-0005, Japan. yoshinori.takei@med.toho-u.ac.jp., Amagase Y; Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 4-20-1 Nasahara, Takatsuki, Osaka, 569-1094, Japan., Goto A; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo, 143-8540, Japan., Kambayashi R; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo, 143-8540, Japan., Izumi-Nakaseko H; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo, 143-8540, Japan., Hirasawa A; Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimo adachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan., Sugiyama A; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-Ku, Tokyo, 143-8540, Japan.; YOKOYAMA Kazuya Cancer Research Institute, 2F Ueno Yokoyama Bidg, 1-4-8 Ueno, Taito-Ku, Tokyo, 110-0005, Japan. |
| Source: | GeroScience [Geroscience] 2025 Aug; Vol. 47 (4), pp. 5969-5983. Date of Electronic Publication: 2025 Feb 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2509-2723 |
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| DOI: | 10.1007/s11357-025-01546-4 |