Thymine as potential biomarker to predict 5-FU systemic exposure in patients with gastro-intestinal cancer: a prospective pharmacokinetic study (FUUT-trial).
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| Title: | Thymine as potential biomarker to predict 5-FU systemic exposure in patients with gastro-intestinal cancer: a prospective pharmacokinetic study (FUUT-trial). |
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| Authors: | Hanrath MA; Department of Clinical Pharmacy, Catharina Hospital, Eindhoven, the Netherlands., Banken E; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands.; GROW Research Institute for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands., van den Wildenberg SAH; Department of Clinical Chemistry, Catharina Hospital, Eindhoven, the Netherlands.; Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands., van de Kerkhof D; Department of Clinical Chemistry, Catharina Hospital, Eindhoven, the Netherlands.; Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands., Moes DJAR; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands., Boisdron-Celle M; Department of Oncopharmacology-Pharmacogenetics INSERM U892, Western Cancer Institute Paul Papin, Angers, France., van den Bosch BJC; Department of Clinical Genetics, Clinical Genomics, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands., Bax R; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands., Bet PM; Department of Clinical Pharmacology and Pharmacy, Amsterdam University Medical Center, Amsterdam, the Netherlands., Maring JG; Department of Clinical Pharmacy, Isala, Zwolle, the Netherlands., Creemers GM; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands., van Hellemond IEG; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands., Deenen MJ; Department of Clinical Pharmacy, Catharina Hospital, Eindhoven, the Netherlands. maarten.deenen@catharinaziekenhuis.nl.; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands. maarten.deenen@catharinaziekenhuis.nl. |
| Source: | Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2025 Feb 15; Vol. 95 (1), pp. 34. Date of Electronic Publication: 2025 Feb 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0843 |
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| DOI: | 10.1007/s00280-025-04759-8 |
