Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism.

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Title: Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism.
Authors: Kiper E; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Ben Hur D; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Alfandari D; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Camacho AC; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Wani NA; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Efrat GD; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Morandi MI; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science, Prague, Czech Republic., Goldsmith M; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel., Rotkopf R; Bioinformatics Unit, Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Kamyshinsky R; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel., Deshmukh A; Unité de Biologie de Plasmodium et Vaccins, Institut Pasteur, Université Paris Cité, Paris, France., Binte Zulkifli NE; Unité de Biologie de Plasmodium et Vaccins, Institut Pasteur, Université Paris Cité, Paris, France., Asmari N; École Polytechnique Fédérale de Lausanne, Laboratory for Bio- and Nano-Instrumentation, Lausanne, Switzerland., Penedo M; École Polytechnique Fédérale de Lausanne, Laboratory for Bio- and Nano-Instrumentation, Lausanne, Switzerland., Fantner G; École Polytechnique Fédérale de Lausanne, Laboratory for Bio- and Nano-Instrumentation, Lausanne, Switzerland., Porat Z; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Azuri I; Bioinformatics Unit, Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel., Rosenhek-Goldian I; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel., Chitnis CE; Unité de Biologie de Plasmodium et Vaccins, Institut Pasteur, Université Paris Cité, Paris, France., Shai Y; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel. Electronic address: yechiel.shai@weizmann.ac.il., Regev-Rudzki N; Faculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel. Electronic address: neta.regev-rudzki@weizmann.ac.il.
Source: The Journal of biological chemistry [J Biol Chem] 2025 Apr; Vol. 301 (4), pp. 108298. Date of Electronic Publication: 2025 Feb 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2025.108298