The sV184A Variant in HBsAg Specific to HBV Subgenotype C2 Leads to Enhanced Viral Replication and Apoptotic Cell Death Induced by PERK-eIF2α-CHOP-Mediated ER Stress.

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Title: The sV184A Variant in HBsAg Specific to HBV Subgenotype C2 Leads to Enhanced Viral Replication and Apoptotic Cell Death Induced by PERK-eIF2α-CHOP-Mediated ER Stress.
Authors: Choi YM; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Seoul National University Medical Research Center (SNUMRC), Seoul, Republic of Korea., Kim DH; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea., Cho EJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim Z; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea., Jang J; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea., Kim H; Department of Convergent Bioscience and Informatics, Chungnam National University, Daejeon, Republic of Korea., Yu SJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim BJ; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Seoul National University Medical Research Center (SNUMRC), Seoul, Republic of Korea.; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Liver Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Cancer Research Institute, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center, Seoul, Republic of Korea.; BK21 FOUR Biomedical Science Project, Seoul National University College of Medicine, Seoul, Republic of Korea.
Source: Journal of medical virology [J Med Virol] 2025 Feb; Vol. 97 (2), pp. e70253.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1096-9071
DOI:10.1002/jmv.70253