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Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA.

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Title: Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA.
Authors: Shin Y; Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA., Hedglin M; Department of Chemistry, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: muh218@psu.edu., Murakami KS; Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: kum14@psu.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2025 Apr; Vol. 301 (4), pp. 108342. Date of Electronic Publication: 2025 Feb 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA.
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  Data: <searchLink fieldCode="AU" term="%22Shin+Y%22">Shin Y</searchLink>; Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hedglin+M%22">Hedglin M</searchLink>; Department of Chemistry, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: muh218@psu.edu.<br /><searchLink fieldCode="AU" term="%22Murakami+KS%22">Murakami KS</searchLink>; Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Center for Structural Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: kum14@psu.edu.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2025 Apr; Vol. 301 (4), pp. 108342. <i>Date of Electronic Publication: </i>2025 Feb 22.
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  Data: Journal Article; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbc.2025.108342
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      – Code: eng
        Text: English
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        StartPage: 108342
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      – TitleFull: Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA.
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            NameFull: Shin Y
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              Text: 2025 Apr
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              Y: 2025
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