Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes.

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Title: Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypes.
Authors: Simmons DA; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Selvaraj S; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Chen T; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Cao G; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Camelo TS; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., McHugh TLM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Gonzalez S; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Martin RM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Simanauskaite J; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA., Uchida N; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Porteus MH; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Longo FM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.; Wu Tsai Neuroscience Institute, Stanford University, Stanford, CA 94305, USA.
Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Jan 22; Vol. 33 (1), pp. 101415. Date of Electronic Publication: 2025 Jan 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2329-0501
DOI:10.1016/j.omtm.2025.101415