Salicylate-Elicited Activation of AMP-Activated Protein Kinase Directly Triggers Degradation of C-Myc in Colorectal Cancer Cells.

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Title: Salicylate-Elicited Activation of AMP-Activated Protein Kinase Directly Triggers Degradation of C-Myc in Colorectal Cancer Cells.
Authors: Matos ALSA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; CAPES Foundation, Ministry of Education of Brazil, Brasília DF 70040-020, Brazil., Ovens AJ; Metabolic Signalling Laboratory, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia., Jakobsen E; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Iglesias-Gato D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Bech JM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Sino-Danish Center for Education and Research, Aarhus University, 8000 Aarhus, Denmark., Friis S; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Bak LK; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Department of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, 2600 Glostrup, Denmark.; Translational Research Center (TRACE), Copenhagen University Hospital-Rigshospitalet, 2600 Glostrup, Denmark., Madsen GI; Department of Pathology, Odense University Hospital, 5000 Odense, Denmark., Oakhill JS; Metabolic Signalling Laboratory, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia., Puustinen P; Cell Death and Metabolism, Danish Cancer Society Research Center (DCRC), 2100 Copenhagen, Denmark., Moreira JMA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Source: Cells [Cells] 2025 Feb 17; Vol. 14 (4). Date of Electronic Publication: 2025 Feb 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2073-4409
DOI:10.3390/cells14040294