PBRM1 directs PBAF to pericentromeres and protects centromere integrity.

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Title: PBRM1 directs PBAF to pericentromeres and protects centromere integrity.
Authors: Lane KA; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Harrod A; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Wu L; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Roumeliotis TI; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Feng H; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK.; The Francis Crick Institute; London, London, UK., Foo S; Division of Radiotherapy and Imaging, The Institute of Cancer Research; London, London, UK., Begg KAG; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Schiavoni F; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Amin N; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Zenke FT; Merck KGaA, Biopharma R&D, Translational Innovation Platform Oncology, Darmstadt, Germany., Melcher AA; Division of Radiotherapy and Imaging, The Institute of Cancer Research; London, London, UK., Choudhary JS; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK., Downs JA; Division of Cell and Molecular Biology, The Institute of Cancer Research; London, London, UK. Jessica.Downs@icr.ac.uk.
Source: Nature communications [Nat Commun] 2025 Feb 26; Vol. 16 (1), pp. 1980. Date of Electronic Publication: 2025 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57277-9