Liquid Biopsy for Enhanced Specificity in Identifying Somatic Mutations in Aggressive Non-Hodgkin Large B-Cell Lymphoma: A Comparative Study of Cell-Free DNA and Formalin-Fixed Paraffin-Embedded Tissue.

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Title: Liquid Biopsy for Enhanced Specificity in Identifying Somatic Mutations in Aggressive Non-Hodgkin Large B-Cell Lymphoma: A Comparative Study of Cell-Free DNA and Formalin-Fixed Paraffin-Embedded Tissue.
Authors: Vimalathas G; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark., Cédile O; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Haematology, Odense University Hospital, Odense, Denmark.; CITCO, Centre for Cellular Immunotherapy of Haematological Cancer Odense, Odense University Hospital, Odense, Denmark.; OPEN, Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark., Kjeldsen MLG; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Haematology, Odense University Hospital, Odense, Denmark., Thomassen M; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Clinical Genome Center, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Møller MB; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Pathology, Odense University Hospital, Odense, Denmark., Nyvold CG; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Haematology, Odense University Hospital, Odense, Denmark.; CITCO, Centre for Cellular Immunotherapy of Haematological Cancer Odense, Odense University Hospital, Odense, Denmark.; OPEN, Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark., Hansen MH; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Haematology, Odense University Hospital, Odense, Denmark.; CITCO, Centre for Cellular Immunotherapy of Haematological Cancer Odense, Odense University Hospital, Odense, Denmark., Larsen TS; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Haematology-Pathology Research Laboratory, Research Unit for Haematology and Research Unit for Pathology, University of Southern Denmark and Odense University Hospital, Odense, Denmark.; Department of Haematology, Odense University Hospital, Odense, Denmark.; CITCO, Centre for Cellular Immunotherapy of Haematological Cancer Odense, Odense University Hospital, Odense, Denmark.
Source: International journal of laboratory hematology [Int J Lab Hematol] 2025 Aug; Vol. 47 (4), pp. 669-679. Date of Electronic Publication: 2025 Feb 27.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 101300213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-553X (Electronic) Linking ISSN: 17515521 NLM ISO Abbreviation: Int J Lab Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1751-553X
DOI:10.1111/ijlh.14454