HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.

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Title: HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.
Authors: Jiang Q; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Braun DA; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Yale Center of Cellular and Molecular Oncology, Yale School of Medicine, New Haven, CT 06511, USA., Clauser KR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Ramesh V; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Shirole NH; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Duke-Cohan JE; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Nabilsi N; TScan Therapeutics, Waltham, MA 02451, USA., Kramer NJ; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Forman C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Lippincott IE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Klaeger S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Phulphagar KM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Chea V; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Kim N; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Vanasse AP; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Saad E; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Parsons T; TScan Therapeutics, Waltham, MA 02451, USA., Carr-Reynolds M; TScan Therapeutics, Waltham, MA 02451, USA., Carulli I; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Pinjusic K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Jiang Y; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Li R; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Syamala S; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Rachimi S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Verzani EK; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Stevens JD; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA., Lane WJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA., Camp SY; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Meli K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Pappalardi MB; Cancer Epigenetics Research Unit, Oncology, GSK, Collegeville, PA 19426, USA., Herbert ZT; Molecular Biology Core Facilities, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Qiu X; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Cejas P; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Long HW; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Shukla SA; Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Choueiri TK; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Churchman LS; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Abelin JG; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA., Gurer C; TScan Therapeutics, Waltham, MA 02451, USA., MacBeath G; TScan Therapeutics, Waltham, MA 02451, USA., Childs RW; Laboratory of Transplantation Immunotherapy, Cellular and Molecular Therapeutics Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA., Carr SA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address: scarr@broad.mit.edu., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Computer Science, Metropolitan College, Boston University, Boston, MA 02215, USA; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark 2800 Lyngby, Denmark. Electronic address: derin_keskin@dfci.harvard.edu., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address: catherine_wu@dfci.harvard.edu., Kaelin WG Jr; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: william_kaelin@dfci.harvard.edu.
Source: Cell [Cell] 2025 Apr 03; Vol. 188 (7), pp. 1807-1827.e34. Date of Electronic Publication: 2025 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4172
DOI:10.1016/j.cell.2025.01.046