Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.

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Title: Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.
Authors: Johri S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Bi K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Titchen BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Harvard Graduate Program in Biological and Biomedical Sciences, Boston, MA, USA., Fu J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Conway J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Harvard Graduate Program in Bioinformatics and Integrative Genomics, Boston, MA, USA., Crowdis JP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vokes NI; Department of Thoracic and Head and Neck Oncology, MD Anderson Cancer Center, Houston, TX, USA.; Department of Genomic Medicine, MD Anderson Cancer Center, Houston, TX, USA., Fan Z; Division of Hematology/Oncology, University of California, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, CA, USA., Fong L; Division of Hematology/Oncology, University of California, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, CA, USA., Park J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Liu D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., He MX; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. eliezerm_vanallen@dfci.harvard.edu.; Broad Institute of Harvard and MIT, Cambridge, MA, USA. eliezerm_vanallen@dfci.harvard.edu.
Source: Nature communications [Nat Commun] 2025 Mar 01; Vol. 16 (1), pp. 2090. Date of Electronic Publication: 2025 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57377-6