Gas6 induces AIM to suppress acute lung injury in mice by inhibiting NLRP3 inflammasome activation and inducing autophagy.

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Title: Gas6 induces AIM to suppress acute lung injury in mice by inhibiting NLRP3 inflammasome activation and inducing autophagy.
Authors: Jeong S; Department of Physiology, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.; Inflammation-Cancer Microenvironment Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Yang K; Department of Physiology, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.; Inflammation-Cancer Microenvironment Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Lee YJ; Department of Physiology, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.; Inflammation-Cancer Microenvironment Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Park JW; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Park EM; Department of Pharmacology, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Kang JL; Department of Physiology, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.; Inflammation-Cancer Microenvironment Research Center, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2025 Feb 17; Vol. 16, pp. 1523166. Date of Electronic Publication: 2025 Feb 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1523166